Four distinct stories of progress show how a challenge once considered unsolvable was addressed: Sending a man to the moon, sequencing the rice genome, making medicine personal and reducing traffic congestion. Across the diversity of these examples, the film reveals how progress was made possible by a combination of people and technology, and by taking a distinct approach to making the world work better -- seeing, mapping, understanding, believing and acting. Today, this very approach can be used to tackle challenges large and small.